A parylene bellows electrochemical actuator for intraocular drug delivery

Author

Li, P.-Y. ; Sheybani, R. ; Kuo, J.T.W. ; Meng, E.

Author_Institution

Dept. of Electr. Eng., Univ. of Southern California, Los Angeles, CA, USA

fYear

2009

fDate

21-25 June 2009

Firstpage

1461

Lastpage

1464

Abstract

The first electrochemical actuator with a parylene bellows for intraocular drug delivery is presented in which the bellows separates the electrolysis actuation chamber from the drug reservoir. The parylene bellows was fabricated using a novel polyethylene glycol (PEG)-molding process and mechanically characterized. Optimization of the gas generation efficiency of the actuators was performed. We achieved an efficiency approaching 80% and over 1.5 mm deflection with our actuator. Wireless operation was also demonstrated.

Keywords

actuators; bellows; bioMEMS; drug delivery systems; electrolysis; moulding; polymers; PEG; drug reservoir; electrochemical actuator; electrolysis actuation chamber; gas generation efficiency; intraocular drug delivery; molding process; parylene bellows; polyethylene glycol; wireless operation; Actuators; Bellows; Biomembranes; Drug delivery; Electrochemical processes; Electrodes; Energy consumption; In vivo; Reservoirs; Tensile stress; Bellows; Drug Delivery Device; Electrolysis Pump; Intraocular Implant;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International

Conference_Location

Denver, CO

Print_ISBN

978-1-4244-4190-7

Electronic_ISBN

978-1-4244-4193-8

Type

conf

DOI

10.1109/SENSOR.2009.5285819

Filename

5285819