DocumentCode
1933016
Title
Revealing Significant Biological Knowledge via Gene Ontologies and Pathways
Author
Blazadonakis, Michalis E. ; Zervakis, Michalis
Author_Institution
Dept. of Electron. & Comput. Eng., Tech. Univ. of Crete, Chania
Volume
1
fYear
2008
fDate
27-30 May 2008
Firstpage
169
Lastpage
172
Abstract
Many scientific works in the field of bioinformatics and marker selection deal with the problem of deriving a gene signature with significant statistical properties without paying much attention on the biological aspect of the produced result. In this paper we assess the problem of revealing possible significant knowledge which might be hidden under a given gene signature, using previous biological information provided through gene ontologies and pathways.
Keywords
biology computing; cellular biophysics; genetics; molecular biophysics; ontologies (artificial intelligence); bioinformatics; gene ontologies; gene pathways; gene signature; marker selection; Bioinformatics; Biology computing; Biomedical computing; Biomedical engineering; Biomedical informatics; Breast cancer; Differential equations; Knowledge engineering; Neurons; Ontologies; DNA microarray; Gene Ontologies; Gene Signature; Marker Selection; Pathways; Survival Prediction;
fLanguage
English
Publisher
ieee
Conference_Titel
BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on
Conference_Location
Sanya
Print_ISBN
978-0-7695-3118-2
Type
conf
DOI
10.1109/BMEI.2008.219
Filename
4548657
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