Ex vivo tissue shrinking in microwave thermal ablation

Author

Farina, L. ; Amabile, C. ; Nissenbaum, Y. ; Cavagnaro, M. ; Lopresto, V. ; Pinto, R. ; Tosoratti, N. ; Cassarino, S. ; Weiss, N. ; Goldberg, S.N.

Author_Institution

Dept. of Inf. Eng., Sapienza Univ. of Rome, Rome, Italy

fYear

2015

fDate

13-17 April 2015

Firstpage

1

Lastpage

4

Abstract

Aim of this study was to characterize the changes occurring in tissues undergoing microwave ablation, in order to more accurately predict the actual treated volume. Different experiments were conducted in restricted samples (10-40 mm side cubes) and in large samples of ex-vivo bovine liver, varying the deposited energy (60 W at 2.45 GHz, applied for 1-10 min). A comparison between pre- and post-ablation dimensions was conducted, pointing out a substantial shrinkage, non-uniform over time and space, asymmetrical along the microwave antenna axis and perpendicularly to it. The obtained results show a complex tissue behavior and a correlation between the carbonized area and the contraction phenomenon.

Keywords

biothermics; cancer; liver; radiation therapy; tumours; actual treated volume; carbonized area; complex tissue behavior; contraction phenomenon; deposited energy; ex vivo tissue shrinking; ex-vivo bovine liver; frequency 2.45 GHz; microwave antenna axis; microwave thermal ablation; post-ablation dimensions; power 60 W; preablation dimensions; size 10 mm to 40 mm; substantial shrinkage; time 1 min to 10 min; Biological tissues; Bovine; Correlation; Electromagnetic heating; Liver; Microwave antennas; ex vivo; microwave ablation; tissue shrinkage;

fLanguage

English

Publisher

ieee

Conference_Titel

Antennas and Propagation (EuCAP), 2015 9th European Conference on

Conference_Location

Lisbon

Type

conf

Filename

7228771