Endoscopic PDT applications of intense femtosecond laser pulses through hollow-fibers and graded-index multimode fibers

Author

Kamino, L. ; Hagiwara, Y. ; Shimada, T. ; Obara, M. ; Hongo, A.

Author_Institution

Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama, Japan

Volume

2

fYear

2004

fDate

7-11 Nov. 2004

Firstpage

833

Abstract

The paper reports on the study of intense femtosecond laser delivery through small-core, 320-μm hollow fibers and through large core graded-index optical fibers. The work also demonstrates the feasibility of endoscopic cancer treatment with PDT excited by fiber delivered, intense Ti:sapphire femtosecond laser pulses. The Ti:sapphire laser excitation of photofrin and indocyanine green (ICG) is studied in vitro experiment.

Keywords

cancer; endoscopes; gradient index optics; high-speed optical techniques; laser applications in medicine; optical fibres; photodynamic therapy; 320 mum; Al₂O₃:Ti; Ti:sapphire femtosecond laser pulses; core graded-index optical fibers; endoscopic PDT; endoscopic cancer treatment; graded-index multimode fibers; hollow-fibers; indocyanine green; photofrin; Fiber lasers; Laser beams; Laser excitation; Laser modes; Optical fiber cables; Optical fiber dispersion; Optical fibers; Optical pulses; Ultrafast electronics; Ultrafast optics;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Society, 2004. LEOS 2004. The 17th Annual Meeting of the IEEE

Print_ISBN

0-7803-8557-8

Type

conf

DOI

10.1109/LEOS.2004.1363499

Filename

1363499