Deformable boundary finding influenced by region homogeneity

Accurately segmenting and quantifying structures is a key issue in biomedical image analysis. The two conventional methods of image segmentation, region-based segmentation and boundary finding, often suffer from a variety of limitations. We propose a method which endeavors to integrate the two approaches in an effort to form a unified approach that is robust to noise and poor initialization. Our approach uses Green´s theorem to derive the boundary of a homogeneous region-classified area in the image and integrates this with a grey-level-gradient-based boundary finder. This combines the perceptual notions of edge/shape information with gray level homogeneity