DocumentCode
2078119
Title
Methods for estimation of demographic parameters from DNA sequence samples
Author
Polanski, Andrzej ; Kimmel, Marek
Author_Institution
Dept. of Stat., Rice Univ., Houston, TX, USA
Volume
5
fYear
2002
fDate
2002
Firstpage
3472
Abstract
The paper shows basic mathematical methodology of modeling genetic neutral evolution, including Fisher-Wright process statistics, appropriate models of mutation and coalescence method, and overviews recent results in the area. The basic approach is the use of maximum likelihood techniques. However due to computational problems, other more intuitive or approximate methods are also of great importance.
Keywords
DNA; computational complexity; demography; evolution (biological); maximum likelihood estimation; DNA sequence samples; Fisher-Wright process statistics; coalescence method; computational problems; demographic parameter estimation; genetic neutral evolution; maximum likelihood techniques; mutation; Automation; Biological system modeling; DNA; Demography; Evolution (biology); Genetic mutations; Mathematical model; Parameter estimation; Sequences; Statistics;
fLanguage
English
Publisher
ieee
Conference_Titel
American Control Conference, 2002. Proceedings of the 2002
ISSN
0743-1619
Print_ISBN
0-7803-7298-0
Type
conf
DOI
10.1109/ACC.2002.1024464
Filename
1024464
Link To Document