Spatial scan of light intensity by retinal rod cells

Author

Sim, Nigel ; Bessarab, Dmitri ; Jones, C. Michael ; Krivitsky, Leonid

Author_Institution

Data Storage Inst., Agency for Sci. Technol. & Res., Singapore, Singapore

fYear

2011

fDate

22-26 May 2011

Firstpage

1

Lastpage

1

Abstract

The optimization of coupling efficiency of light emerging from the tip of a tapered single mode fiber within a live retinal rod cell of adult frog Xenopus laevis is studied. Results show a Gaussian profile of the intensity distribution of light emitted from a single mode fibre. The capability of scanning the spatial intensity distribution of light field emerging from the tip of a fiber allows direct estimation of the coupling efficiency of light with retinal rods, which is highly relevant for precise characterisation of the cell response to optical stimulation in various biological tasks.

Keywords

bio-optics; biological techniques; cellular biophysics; optimisation; Gaussian profile; adult frog Xenopus laevis; cell response; light coupling efficiency; light intensity distribution; light intensity spatial scan; live retinal rod cell; optical stimulation; optimization; single mode fiber; spatial intensity distribution;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference on and 12th European Quantum Electronics Conference

Conference_Location

Munich

ISSN

Pending

Print_ISBN

978-1-4577-0533-5

Electronic_ISBN

Pending

Type

conf

DOI

10.1109/CLEOE.2011.5943695

Filename

5943695