DocumentCode
2092424
Title
Study on the influence of Konjac glucomannan on assaying domperidone in orally disintergrating tablets
Author
Yu, Yuhong ; Pan, Lin ; Ma, Jianlong ; Dai, Rongji ; Deng, Yulin
Author_Institution
Beijing Inst. of Technol., Beijing
fYear
2007
fDate
23-27 May 2007
Firstpage
1824
Lastpage
1827
Abstract
To evaluate the influence of Konjac glucomannan (KGM) on assaying domperidone in orally disintergrating tablets, We established an RP-HPLC method for the determination of domperidone in dompoeridone orally disintergrating tablets. Then KGM was added to the prescription. Good resolution was obtained after the sample was destroyed by acid, alkali and heat. The results suggested that KGM had the potential to be used in drug delivery systems.
Keywords
chromatography; drugs; organic compounds; Konjac glucomannan; RP-HPLC method; domperidone; drug delivery system; orally disintergrating tablet; reverse phase high-performance liquid chromatography; Blood; Drug delivery; Humans; Immune system; Intestines; Methanol; Pharmaceuticals; Polymers; Sugar industry; Temperature;
fLanguage
English
Publisher
ieee
Conference_Titel
Complex Medical Engineering, 2007. CME 2007. IEEE/ICME International Conference on
Conference_Location
Beijing
Print_ISBN
978-1-4244-1077-4
Electronic_ISBN
978-1-4244-1078-1
Type
conf
DOI
10.1109/ICCME.2007.4382062
Filename
4382062
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