Electro-mechanical modeling of the myocardium: coupling and feedback mechanisms

Author

Sachse, F.B. ; Seemann, G. ; Riedel, C. ; Werner, C.D. ; Dössel, O.

Author_Institution

Inst. fur Biomedizinische Technik, Karlsruhe Univ., Germany

fYear

2001

fDate

2001

Firstpage

161

Lastpage

164

Abstract

Computer-aided simulations of the heart provide knowledge for cardiological diagnosis and therapy. A model of the myocardium is presented which allows the reconstruction of electrical and mechanical processes with the inclusion of feedback mechanisms. The model combines detailed models of cellular electrophysiology and force development with models of the electrical current flow and the mechanical behavior of the myocardium. The results of simulations show the connection between the electrical excitation process and the following mechanical deformation in a 3D anisotropic area of the myocardium

Keywords

bioelectric phenomena; biomechanics; cardiology; deformation; digital simulation; electromechanical effects; feedback; medical computing; muscle; physiological models; 3D anisotropic area; cardiological diagnosis; cellular electrophysiology; computer-aided simulations; coupling mechanisms; electrical current; electrical excitation process; electromechanical modeling; feedback mechanisms; force development; heart; mechanical deformation; myocardium; patient therapy; Anisotropic magnetoresistance; Cardiology; Cells (biology); Couplings; Deformable models; Feedback; Finite element methods; Heart; Myocardium; Poisson equations;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 2001

Conference_Location

Rotterdam

ISSN

0276-6547

Print_ISBN

0-7803-7266-2

Type

conf

DOI

10.1109/CIC.2001.977616

Filename

977616