Multi-element linear array of silicon detectors for imaging beta emitting compounds in the coronary arteries

Author

Janecek, Martin ; Hoffman, Edward J. ; Tull, Carolyn R. ; Patt, Bradley E. ; Iwanczyk, Jan S. ; MacDonald, Lawrence ; Maculewicz, George J. ; Ghazarossian, Vartan ; Strauss, H. William

Author_Institution

David Geffen Sch. of Medicine, California Univ., Los Angeles, CA, USA

Volume

3

fYear

2002

fDate

10-16 Nov. 2002

Firstpage

1416

Abstract

Coronary artery disease (CAD) is the leading cause of death in most developed countries. A large portion of CAD is caused by rupture of unstable plaque, which is not detectable by current diagnostic methods. By labeling the unstable plaque with beta emitting radioisotopes, it is possible to detect these plaques with a very narrow in situ detector system. Our intra-vascular detector system is an imaging device, consisting of several silicon detectors mounted on a flexible PC-board inside of a 1.6 mm diameter catheter. The catheter shields the detectors from outside light and enables the device to he guided to the coronary arteries during an angiography session. Each silicon detector consists of a linear array of 20 square pixels,with pixel dimensions of 0.45 mm × 0.45 mm.

Keywords

angiocardiography; beta-ray detection; diseases; radioisotope imaging; silicon radiation detectors; 0.45 mm; 1.6 mm; Si; Si detectors; angiography; beta emitting compounds imaging; coronary artery disease; diagnostic methods; multielement linear array; unstable plaque; Angiography; Arteries; Catheters; Coronary arteriosclerosis; Detectors; Diseases; Optical imaging; Resistors; Sensor arrays; Silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2002 IEEE

Print_ISBN

0-7803-7636-6

Type

conf

DOI

10.1109/NSSMIC.2002.1239586

Filename

1239586