Effects of attenuation correction and 3D-reconstruction algorithms on brain lesions detectability

Author

Baghaei, Hossain ; Uribe, Jorge ; Li, Hongdi ; Wang, Yu ; Liu, Yaqiang ; Xing, Tao ; Farrell, Rocio ; Wong, WaiHoi

Author_Institution

M.D. Anderson Cancer Center, Texas Univ., Houston, TX, USA

Volume

3

fYear

2002

fDate

10-16 Nov. 2002

Firstpage

1529

Abstract

We compared lesion detectability in the brain images reconstructed with the three-dimensional (3-D) reprojection algorithm, with and without attenuation correction, and with the 3-D ordered subsets expectation maximization (OSEM) algorithm with and without post-filtering. For this purpose, three small lesion phantoms with diameters of 3, 5 and 8.6 mm were embedded into the Hoffman brain phantom. The approximate ratio of the activity concentration in the lesions to the surrounding brain gray matter was ranging from 1.5 to 10. We used the high-resolution MDAPET, a prototype 3D-PET camera, to scan the phantoms.

Keywords

brain; cameras; image reconstruction; medical image processing; optimisation; phantoms; positron emission tomography; 3 mm; 3D ordered subsets expectation maximization; 3D-reconstruction algorithms; 5 mm; 8.6 mm; Hoffman brain phantom; OSEM; attenuation correction effects; brain gray matter; brain lesions detectability; high-resolution MDAPET; positron emission tomography; prototype 3D-PET camera; Attenuation; Cameras; Cancer; Crystals; Detectors; Image reconstruction; Imaging phantoms; Lesions; Positron emission tomography; Prototypes;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2002 IEEE

Print_ISBN

0-7803-7636-6

Type

conf

DOI

10.1109/NSSMIC.2002.1239612

Filename

1239612