• DocumentCode
    2218496
  • Title

    Stability robust analysis of calcium in neuron

  • Author

    Lei, Yin ; Bin, Zhu ; Jia-li, Bao ; Rui, Chen ; Chao-yang, Zhu

  • Author_Institution
    Sch. of Med., Zhejiang Univ., Hangzhou
  • fYear
    2008
  • fDate
    30-31 May 2008
  • Firstpage
    387
  • Lastpage
    390
  • Abstract
    In this paper, the calcium system in a neuron is a highly non-linear system. It could be delineated by unknown bounded model that is a subject of robustness analysis. We view a neural cell as a biological system and glutamate as a kind of chemical effect that disturbs the calcium homeostasis of the neural cell. Then we use robustness analysis to study the stable robustness of Ca2+ in neurons after disturbed by glutamate in five concentrations. So the conclusion is that calcium system in a neuron is a dynamic system and its stable robustness reflects the persistence of structure, state and behavior of the system. If the deviation from the steady-state caused by larger perturbations is small enough, the stable robustness of the system is strong. Otherwise, it is weak.
  • Keywords
    biochemistry; cellular biophysics; neurophysiology; stability; Ca; calcium homeostasis; chemical effect; dynamic system; glutamate; neural cell; neuron; nonlinear system; stability robust analysis; Biological system modeling; Biological systems; Calcium; Cells (biology); Chemicals; Neurons; Robust stability; Robustness; Stability analysis; Steady-state; Biology Robustness; Calcium; Neuron;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information Technology and Applications in Biomedicine, 2008. ITAB 2008. International Conference on
  • Conference_Location
    Shenzhen
  • Print_ISBN
    978-1-4244-2254-8
  • Electronic_ISBN
    978-1-4244-2255-5
  • Type

    conf

  • DOI
    10.1109/ITAB.2008.4570602
  • Filename
    4570602