Model-based approach to the localization of infarction

Author

Farina, D. ; Dössel, O.

Author_Institution

Univ. Karlsruhe (TH), Karlsruhe

fYear

2007

fDate

Sept. 30 2007-Oct. 3 2007

Firstpage

173

Lastpage

176

Abstract

A model-based approach to noninvasively determine the location and size of the infarction scar is proposed, that in addition helps to estimate the risk of arrhythmias. The approach is based on the optimization of an electrophysiological heart model with an introduced infarction scar to fit the multichannel ECG measured on the surface of the patient´s thorax. This model delivers the distributions of transmembrane voltages (TMV) within the ventricles during a single heart cycle. The forward problem of electrocardiography is solved in order to obtain the simulated ECG of the patient. This ECG is compared with the measured one, the difference is used as the criterion for optimization of model parameters, which include the site and size of infarction scar.

Keywords

bioelectric phenomena; cellular automata; diseases; electrocardiography; medical computing; muscle; physiological models; cellular automaton based model; electrocardiography; electrophysiological heart model; infarction scar localization; model-based approach; multichannel ECG; myocardial infarction; transmembrane voltage distribution; Automata; Electrocardiography; Electrophysiology; Fibrillation; Heart; Myocardium; Size measurement; Surface fitting; Thorax; Voltage;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 2007

Conference_Location

Durham, NC

ISSN

0276-6547

Print_ISBN

978-1-4244-2533-4

Electronic_ISBN

0276-6547

Type

conf

DOI

10.1109/CIC.2007.4745449

Filename

4745449