EPOCH® and ePRISM®: A web-based translational framework for bridging outcomes research and clinical practice

In an era where novel clinical, biochemical, genetic and imaging determinants impacting patient outcomes are being continuously discovered, the field of outcomes research offers clinicians and patients the potential to make better informed health care decisions through the use of sophisticated risk-adjustment models that incorporate patientspsila unique clinical characteristics. EPOCH^reg and ePRISM^reg comprise a novel application suite for delivering complex risk-adjustment models to the bedside and are currently in use at multiple medical centers. An intuitive visual interface for building models allows outcomes researchers to rapidly translate prediction models into web-based decision support and reporting tools. A flexible XML web services architecture facilitates integration with existing clinical information systems, allows for remote access to the modeling engine, and allows models to be exported across systems via the Predictive Model Markup Language standard.