THz-TDS studies on proteins and molecular complexes in solutions

Author

Tominaga, Keisuke ; Kawaguchi, Shintaro ; Shibata, Mikihiro ; Kandori, Hideki ; Dutta, Partha

fYear

2009

fDate

21-25 Sept. 2009

Firstpage

1

Lastpage

3

Abstract

We have investigated low-frequency spectra of various systems in condensed phases by terahertz time-domain spectroscopy (THz-TDS). Low-frequency dynamics of bacteriorhodopsin is studied by changing the amount of hydration and temperature. A hydrated sample shows a sudden change in the THz spectrum at -40degC, although a dried sample does not show any change during the temperature change. For the solute/solvent systems we measured solutions of polar solutes in non-polar solvents to extract microscopic information on the interaction between the solute and solvent.

Keywords

proteins; solvation; terahertz spectroscopy; terahertz wave spectra; bacteriorhodopsin hydration; bacteriorhodopsin low frequency dynamics; bacteriorhodopsin temperature; low frequency spectra; nonpolar solvents; polar solutes; solute-solvent systems; solution phase molecular complex spectroscopy; solution phase protein spectroscopy; temperature -40 degC; terahertz time domain spectroscopy; Absorption; Crystals; Frequency; Proteins; Refractive index; Resonance; Solvents; Spectroscopy; Temperature; Time domain analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared, Millimeter, and Terahertz Waves, 2009. IRMMW-THz 2009. 34th International Conference on

Conference_Location

Busan

Print_ISBN

978-1-4244-5416-7

Electronic_ISBN

978-1-4244-5417-4

Type

conf

DOI

10.1109/ICIMW.2009.5325522

Filename

5325522