DocumentCode
2378613
Title
Selecting SNPs for pharmacogenomic association study
Author
Ahn, TaeJin ; Park, Kyunghee ; Son, Dae-Soon ; Nam Huh ; Lee, Kyusang ; Bae, Taejung ; Park, Jung-Sun ; Oh, So-Hee ; Lee, Ji-Hyun ; Rho, Kyoohyuong ; Kim, Sung ; Park, Tae Sung
Author_Institution
Genetic Anal. Group, Samsung Adv. Inst. of Technol., Suwon, South Korea
fYear
2010
fDate
18-18 Dec. 2010
Firstpage
312
Lastpage
317
Abstract
SNP genotyping device is an essential tool in the upcoming era of personal genome, personalized medicine. Human genome has more than 10 million SNPs while conventional SNP genotyping device can only hold 1 million SNPs. Thus intelligent SNP contents selection is required to maximize the value of SNP genotyping device. Here, we developed a new selection algorithm and applied this method to design genotyping contents for cancer and pharmacogenomic association study. This approach significantly increased the product value when compared to contents of competitive SNP genotyping product.
Keywords
cancer; genetics; genomics; medical computing; SNP; cancer; genotyping; pharmacogenomic association; SNP selection; association study; candidate gene approach;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine Workshops (BIBMW), 2010 IEEE International Conference on
Conference_Location
Hong, Kong
Print_ISBN
978-1-4244-8303-7
Electronic_ISBN
978-1-4244-8304-4
Type
conf
DOI
10.1109/BIBMW.2010.5703820
Filename
5703820
Link To Document