• DocumentCode
    2386236
  • Title

    Widefield fluorescence sectioning with HiLo microscopy

  • Author

    Mertz, Jerome ; Lim, Daryl ; Chu, Kengyeh K. ; Bozinovic, Nenad ; Ford, Timothy

  • Author_Institution
    Dept. of Biomed. Eng., Boston Univ., Boston, MA, USA
  • fYear
    2009
  • fDate
    3-6 Sept. 2009
  • Firstpage
    3229
  • Lastpage
    3230
  • Abstract
    HiLo microscopy is a widefield fluorescence imaging technique that provides depth discrimination by combining two images, one with non-uniform illumination and one with uniform illumination. We discuss the theory of this technique and a variety of practical implementations in brain-tissue imaging and fluorescence endomicroscopy.
  • Keywords
    biomedical optical imaging; brain; fluorescence; optical microscopy; HiLo microscopy; brain-tissue imaging; depth discrimination; fluorescence endomicroscopy; nonuniform illumination; uniform illumination; widefield fluorescence sectioning; Animals; Equipment Design; Humans; Image Processing, Computer-Assisted; Microscopy, Confocal; Microscopy, Fluorescence; Optics and Photonics; Reproducibility of Results;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
  • Conference_Location
    Minneapolis, MN
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-3296-7
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2009.5333166
  • Filename
    5333166