Stretchable bioelectrodes

Author

Ziaie, B.

Author_Institution

Sch. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN, USA

fYear

2009

fDate

3-6 Sept. 2009

Firstpage

1049

Lastpage

1052

Abstract

In this paper, we present a stretchable electrode array for studying cell behavior subjected to mechanical strain. The electrode array consists of four gold nail-head pins (250 mum tip diameter and 1.75 mm spacing) inserted into a polydimethylsiloxane (PDMS) platform (25.4 times 25.4 mm²). Fusible indium alloy (liquid at room temperature) filled microchannels are used to connect the electrodes to the outside, thus providing the required stretchability. The electrode platform is biocompatible and can withstand strains of up to 40%. We tested these electrodes by repeatedly (100 times) subjecting them to 35% strain and did not notice any failure. We also successfully cultured mice cardiomyocytes onto the platform and performed electrical pacing.

Keywords

bioMEMS; biomechanics; biomedical electrodes; cardiology; cellular biophysics; gold; indium alloys; microelectrodes; microfabrication; Au; InJkJk; cell behavior; cultured mice cardiomyocytes; electrical pacing; fusible indium alloy filled microchannels; gold nail-head pins; mechanical strain; polydimethylsiloxane platform; size 1.75 mm; size 250 mum; stretchable bioelectrode electrode; temperature 293 K to 298 K; Elastic Modulus; Electric Impedance; Electrodes; Epoxy Compounds; Equipment Design; Equipment Failure Analysis; Polymers; Reproducibility of Results; Sensitivity and Specificity;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

Conference_Location

Minneapolis, MN

ISSN

1557-170X

Print_ISBN

978-1-4244-3296-7

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2009.5334302

Filename

5334302