• DocumentCode
    2442208
  • Title

    Accuracy of differential expression detection with compressed microarray images

  • Author

    Xu, Qian ; Jianping Hua ; Xiong, Zixiang ; Bittner, Michael L. ; Dougherty, Edward R.

  • Author_Institution
    Dept of Electr. & Comput. Eng., Texas A & M Univ., College Station, TX
  • fYear
    2006
  • fDate
    28-30 May 2006
  • Firstpage
    43
  • Lastpage
    44
  • Abstract
    Current gene-expression microarrays carry an enormous amount of information. This paper examines lossy SPIHT and JPEG 2000 compression of oligo microarray images and addresses the accuracy of differential expression detection with compressed images. Experiments show that the identification disagreement rate for all genes monotonically increases with the compression ratio, but is still under 1.5% at 20:1 compression with both SPIHT and JPEG 2000.
  • Keywords
    data compression; image coding; JPEG 2000 compression; SPIHT; compressed microarray images; differential expression detection; gene-expression microarrays; oligo microarray images; Arithmetic; Bioinformatics; Genomics; Humans; ISO; Image coding; Image storage; Transform coding; Wavelet coefficients; Wavelet domain;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Genomic Signal Processing and Statistics, 2006. GENSIPS '06. IEEE International Workshop on
  • Conference_Location
    College Station, TX
  • Print_ISBN
    1-4244-0384-7
  • Electronic_ISBN
    1-4244-0385-5
  • Type

    conf

  • DOI
    10.1109/GENSIPS.2006.353147
  • Filename
    4161768