Monitoring of living cells adhesion behavior by means of surface plasmon resonance biosensor

Author

Wang, Chunyan ; Tan, Yingjun ; Yu, Jianru ; Gu, Yin ; Li, Yinghui

Author_Institution

State Key Lab. of Space Med. Fundamentals & Applic., China Astronaut Res. & Training Center, Beijing, China

fYear

2011

fDate

24-26 June 2011

Firstpage

7687

Lastpage

7689

Abstract

Surface plasmon resonance (SPR) sensor provides a useful means to study the concentration change on the sensor chip. In this study, we developed a living cells adhesion behavior monitoring technology, using SPR biosensor to detect the refractive index change induced by the living C6 cells attachment. Combined with the cell images under microscope, the re-distribution of molecules between the cell-matrix during the cell adhesion process was discussed.

Keywords

adhesion; biosensors; cellular biophysics; molecular biophysics; refractive index; surface plasmon resonance; SPR sensor; cell images; cell-matrix; concentration change; living C6 cells attachment; living cell adhesion behavior monitoring; refractive index change; sensor chip; surface plasmon resonance biosensor; Adhesives; Biosensors; Monitoring; Optical surface waves; Optical waveguides; Plasmons; Surface waves; cells adhesion; dynamic; surface plasmon resonance;

fLanguage

English

Publisher

ieee

Conference_Titel

Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on

Conference_Location

Nanjing

Print_ISBN

978-1-4244-9172-8

Type

conf

DOI

10.1109/RSETE.2011.5966155

Filename

5966155