DocumentCode
2480866
Title
P5B-8 Self-Trapping of Microbubbles to Surface of Target
Author
Yamakoshi, Yoshiki
Author_Institution
Gunma Univ., Kiryu
fYear
2007
fDate
28-31 Oct. 2007
Firstpage
2215
Lastpage
2218
Abstract
A novel method of self-trapping of micro bubbles is proposed in order to trap the bubbles to the surface of target. This method uses micro bubble aggregation between an actual bubble and the mirror bubble that is located at symmetry position for the surface of the target. Nonlinear oscillation of micro bubble in conjunction with the secondary ultrasonic wave radiated from the bubble produces the Bjerknes force which acts as a trapping force to the target surface. Once the bubble is trapped, the nonlinear oscillation of already trapped bubble promotes the further tapping to the target surface. A condition for minimum separation between the neighboring bubbles is derived, which is required to start the trapping. Experiments are carried out using contrast agent micro bubbles. Silicone resin and agar gel phantoms are examined as targets.
Keywords
biomedical ultrasonics; bubbles; drug delivery systems; phantoms; ultrasonic effects; ultrasonic imaging; Bjerknes force; agar gel phantoms; contrast agent microbubbles; microbubble aggregation; microbubbles self-trapping; nonlinear oscillation; secondary ultrasonic wave radiation; silicone resin; target surface; Biomembranes; Cells (biology); Drug delivery; Explosions; Frequency; Mirrors; Payloads; Pharmaceutical technology; Resins; Surface waves;
fLanguage
English
Publisher
ieee
Conference_Titel
Ultrasonics Symposium, 2007. IEEE
Conference_Location
New York, NY
ISSN
1051-0117
Print_ISBN
978-1-4244-1384-3
Electronic_ISBN
1051-0117
Type
conf
DOI
10.1109/ULTSYM.2007.557
Filename
4410130
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