• DocumentCode
    2480866
  • Title

    P5B-8 Self-Trapping of Microbubbles to Surface of Target

  • Author

    Yamakoshi, Yoshiki

  • Author_Institution
    Gunma Univ., Kiryu
  • fYear
    2007
  • fDate
    28-31 Oct. 2007
  • Firstpage
    2215
  • Lastpage
    2218
  • Abstract
    A novel method of self-trapping of micro bubbles is proposed in order to trap the bubbles to the surface of target. This method uses micro bubble aggregation between an actual bubble and the mirror bubble that is located at symmetry position for the surface of the target. Nonlinear oscillation of micro bubble in conjunction with the secondary ultrasonic wave radiated from the bubble produces the Bjerknes force which acts as a trapping force to the target surface. Once the bubble is trapped, the nonlinear oscillation of already trapped bubble promotes the further tapping to the target surface. A condition for minimum separation between the neighboring bubbles is derived, which is required to start the trapping. Experiments are carried out using contrast agent micro bubbles. Silicone resin and agar gel phantoms are examined as targets.
  • Keywords
    biomedical ultrasonics; bubbles; drug delivery systems; phantoms; ultrasonic effects; ultrasonic imaging; Bjerknes force; agar gel phantoms; contrast agent microbubbles; microbubble aggregation; microbubbles self-trapping; nonlinear oscillation; secondary ultrasonic wave radiation; silicone resin; target surface; Biomembranes; Cells (biology); Drug delivery; Explosions; Frequency; Mirrors; Payloads; Pharmaceutical technology; Resins; Surface waves;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Ultrasonics Symposium, 2007. IEEE
  • Conference_Location
    New York, NY
  • ISSN
    1051-0117
  • Print_ISBN
    978-1-4244-1384-3
  • Electronic_ISBN
    1051-0117
  • Type

    conf

  • DOI
    10.1109/ULTSYM.2007.557
  • Filename
    4410130