• DocumentCode
    2493146
  • Title

    Metabolic profiling: definition and use in physiological state classification

  • Author

    Lee, K. ; Hwang, D. ; Yarmush, Martin L. ; Stephanopoulos, G.N.

  • Volume
    3
  • fYear
    2002
  • fDate
    23-26 Oct. 2002
  • Firstpage
    2213
  • Abstract
    Metabolic profiling analyses were performed on metabolite measurements and intracellular fluxes obtained in liver models of injury. Classification of physiological states by projection based discrimination improved with increasing metabolite measurement number and addition of fluxes.
  • Keywords
    biochemistry; biomedical measurement; cellular biophysics; liver; physiological models; physiology; statistical analysis; cellular homeostasis; increasing metabolite measurement number; injury; intracellular fluxes; liver failure; liver models; metabolic profiling; metabolite measurements; physiological state classification; physiological states; Biochemistry; Biological system modeling; Chemical analysis; Chemical engineering; Chemical technology; Extracellular; Hospitals; Injuries; Liver; Principal component analysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-7612-9
  • Type

    conf

  • DOI
    10.1109/IEMBS.2002.1053246
  • Filename
    1053246