Double layer versus single dipole model in the estimation of the site of early ventricular depolarization

In this simulation study the site of earliest activation is estimated using a single reference set of activation data and resulting electrocardiograms (ECGs) to which different noise realizations have been added. The estimated site of earliest ventricular depolarization found by using the single dipole model (SDM) and the one found by using the double layer model (DLM) are compared to the actual site of the reference activation sequence. The results show that the DLM is less sensitive to noise in the data than the SDM