• DocumentCode
    2508935
  • Title

    Feature Selection for Tandem Mass Spectrum Quality Assessment via Sparse Logistical Regression

  • Author

    Ding, Jiarui ; Wu, Fang-Xiang

  • Author_Institution
    Dept. of Mech. Eng., Univ. of Saskatchewan, Saskatoon, SK, Canada
  • fYear
    2009
  • fDate
    11-13 June 2009
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Machine learning algorithms are widely used for quality assessment of tandem mass spectra based on a number of features. However, it is still unclear which features are most relevant to the quality of tandem mass spectra. In this paper, a sparse logistical regression method is proposed for selecting the most relevant features from those features found in the literature. To investigate the performance of the proposed method, experiments are conducted on two datasets. The results show the sparse logistical regression model can effectively select a small number of highly relevant features for tandem mass spectrum quality assessment.
  • Keywords
    biological techniques; biology computing; learning (artificial intelligence); mass spectra; mass spectrometers; regression analysis; feature selection; machine learning; quality assessment; sparse logistical regression; tandem mass spectrum; Biological system modeling; Biomedical engineering; Biomedical measurements; Charge measurement; Current measurement; Machine learning algorithms; Mass spectroscopy; Peptides; Proteins; Quality assessment;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4244-2901-1
  • Electronic_ISBN
    978-1-4244-2902-8
  • Type

    conf

  • DOI
    10.1109/ICBBE.2009.5162855
  • Filename
    5162855