DocumentCode
2523349
Title
EMBRIOSS: ELECTROMAGNETIC BRAIN IMAGING BY OPTIMIZATION IN SPECTRAL SPACE
Author
Vadakkumpadan, Fijoy ; Sun, Yinlong
Author_Institution
Dept. of Comput. Sci., Purdue Univ., West Lafayette, IN
fYear
2007
fDate
12-15 April 2007
Firstpage
1024
Lastpage
1027
Abstract
We propose a new method called electromagnetic brain imaging by optimization in spectral space (EMBRIOSS) for electromagnetic source imaging of the human brain. The method incorporates the physiological knowledge that electrical activities in the brain are spatially coherent and often sparse. For spatial coherency, we confine the solution to a subspace spanned by the low-frequency eigenvectors of a Laplacian of the cortical surface mesh. For sparseness, we apply a p-norm regularization with p < 2. The resulting nonlinear regularization problem is solved efficiently using half-quadratic programming. Through realistic simulations, we have compared our method with existing approaches. The results show that our method performs better
Keywords
Laplace equations; bioelectric phenomena; biomedical imaging; brain models; eigenvalues and eigenfunctions; magnetoencephalography; mesh generation; EMBRIOSS; Laplacian eigenvectors; MEG source signal; brain activities; cortical surface mesh; electrical activities; electromagnetic brain imaging; electromagnetic source imaging; half-quadratic programming; head model; human brain; low-frequency eigenvectors; nonlinear regularization problem; optimization; p-norm regularization; sparseness; spatial coherency; spectral space; Biomedical imaging; Brain modeling; Electroencephalography; Gain measurement; Humans; Linear systems; Magnetic field measurement; Noise measurement; Sensor systems; Spatial coherence;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Conference_Location
Arlington, VA
Print_ISBN
1-4244-0672-2
Electronic_ISBN
1-4244-0672-2
Type
conf
DOI
10.1109/ISBI.2007.357029
Filename
4193463
Link To Document