Review on exhaled volatile organic compounds from lung cancer and advances of E-nose as non-invasive detection method

Author

Thriumani, R. ; Zakaria, A. ; Omar, M.I. ; Adom, Abdul Hamid ; Sharaff, A.Y.M. ; Kamaruddin, L.M. ; Yusuf, N. ; Helmy, K.M.

Author_Institution

Centre of Excellence for Adv. Sensor Technol., Univ. Malaysia Perlis, Jejawi, Malaysia

fYear

2014

fDate

11-12 Aug. 2014

Firstpage

213

Lastpage

218

Abstract

Lung cancer (LC) is known as the most common cancers and becoming the leading cause of cancer related death in human. The high mortality in lung cancer patient occurs because of lack of efficient methods to diagnose the disease at an early stage. In this review, we highlighted the studies conducted on compounds in exhaled air breath and metabolic pathway alteration in lung cancer patient, which may influence the alterations of volatile organic compounds (VOCs) in exhaled air breath. This review has shown that VOCs from exhaled air breath of lung cancer patient has potential to be used as lung cancer biomarker to diagnose lung cancer at primary stage by developing advanced technology of electronic nose system.

Keywords

biochemistry; cancer; electronic noses; lung; organic compounds; patient diagnosis; E-nose; VOC; cancer related death; electronic nose system; exhaled air breath; exhaled volatile organic compounds; lung cancer biomarker; lung cancer diagnosis; lung cancer patient; metabolic pathway alteration; mortality; noninvasive detection method; primary stage; Biochemistry; Cancer; Electronic noses; Lungs; Sensitivity; Volatile organic compounds; electronic nose system; exhaled air breath; lung cancer; metabolic alteration; volatile organic compounds (VOCs);

fLanguage

English

Publisher

ieee

Conference_Titel

Control and System Graduate Research Colloquium (ICSGRC), 2014 IEEE 5th

Conference_Location

Shah Alam

Print_ISBN

978-1-4799-5691-3

Type

conf

DOI

10.1109/ICSGRC.2014.6908724

Filename

6908724