Thermal Adaptability of Proteins on Amino Acid Composition

Author

Zhang, Linsen ; Jin, Xiangyang ; Chen, Feiming ; Lin, Zhengming

Author_Institution

Coll. of Sci., Wuhan Univ. of Sci. & Eng., Wuhan, China

fYear

2009

fDate

11-13 June 2009

Firstpage

1

Lastpage

4

Abstract

This paper is on composition difference of proteins with different thermal adaptability. Statistic analysis of protein sequences and lattice simulation according to the composition differences were done. Differently with the other works on this subject, the composition comparison was based upon hyperthermophilic, thermophilic, mesophilic, psychrotolerantic and psychrophilic proteins together. According to the results, we think that the composition differences of proteins with different thermal adaptability indeed have biological effects of thermal adaptability. The results also show the consistency of the composition difference between thermophilic and psychrophilic proteins and the composition difference between prokaryotic and eukaryotic proteins. This supports the hypothesis of biological evolution from thermophiles.

Keywords

biothermics; evolution (biological); microorganisms; molecular biophysics; proteins; amino acid composition; eukaryotic protein; hyperthermophilic protein; mesophilic protein; prokaryotic protein; protein sequence; psychrophilic protein; psychrotolerantic protein; statistic analysis; thermal adaptability; thermophile biological evolution; thermophilic protein; Amino acids; Biochemistry; Biological system modeling; Hyperthermia; Ocean temperature; Protein engineering; Psychology; Temperature distribution; Thermal engineering; Thermal stability;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on

Conference_Location

Beijing

Print_ISBN

978-1-4244-2901-1

Electronic_ISBN

978-1-4244-2902-8

Type

conf

DOI

10.1109/ICBBE.2009.5163682

Filename

5163682