Effect of non-thermal plasma on loading of tetracycline combined with plga into titania nanotube

Author

Su-Yeon Im ; Seung-Kyun Moon ; Jae-Sung Kwon ; Kwang-Mahn Kim ; Kyoung-Nam Kim ; Yong Hee Kim ; Eun Ha Choi

Author_Institution

Dept. & Res. Inst. of Dental Biomater. & Bioeng., Yonsei Univ., Seoul, South Korea

fYear

2012

fDate

8-13 July 2012

Abstract

Titania nanotube (TNT) is a tube shaped thin film that is fabricated by process known as the anodization and it has been known to exhibit excellent biocompatibility and high surface-to-volume ratio, which makes it ideal structure as a carrier for drugs. However, drug loading on TNT has been limited by narrow diameter of TNT and to overcome this problem, the present study attempted to determine whether plasma treatment of inner TNT surface enhances its hydrophilicity and resultant drug carrying properties.

Keywords

anodisation; biomedical materials; drug delivery systems; drugs; nanofabrication; nanomedicine; nanotubes; plasma materials processing; polymer films; thin films; titanium compounds; PLGA; TiO₂; anodization; biocompatibility; drug carrying properties; drug loading; high surface-volume ratio; hydrophilicity; nonthermal plasma effect; plasma treatment; surface enhances; tetracycline; titania nanotube; tube shaped thin film; Dentistry; Drugs; Educational institutions; Loading; Plasma properties; Surface treatment;

fLanguage

English

Publisher

ieee

Conference_Titel

Plasma Science (ICOPS), 2012 Abstracts IEEE International Conference on

Conference_Location

Edinburgh

ISSN

0730-9244

Print_ISBN

978-1-4577-2127-4

Electronic_ISBN

0730-9244

Type

conf

DOI

10.1109/PLASMA.2012.6383696

Filename

6383696