Characterization of Brownian dynamics induced by glucose using time-domain optical coherence tomography

Author

Li, Jianjun ; Li, Zhifang ; Li, Hui ; Lin, Xiaona

Author_Institution

Key Lab. of Optoelectron. Sci. & Imaging for Med., Fujian Normal Univ., Fuzhou, China

Volume

2

fYear

2011

fDate

15-17 Oct. 2011

Firstpage

685

Lastpage

689

Abstract

Our purpose is to characterize the Brownian motion of glucose concentration in Intralipid solution using time-domain optical coherence tomography (OCT) incorporated with wavelet power spectrum. The results show that the standard deviation (SD) of frequency in the superficial layer, linearly proportional to Brownian diffusion coefficient, is independent of the depth. Our preliminary results demonstrate that SD is inversely proportional to the glucose concentration in Intralipid solution, since the Brownian diffusion coefficient is related to concentration. Thus the SD of frequency in OCT signal is capable of distinguishing the glucose concentration.

Keywords

Brownian motion; biochemistry; biodiffusion; biological techniques; molecular biophysics; optical tomography; organic compounds; Brownian diffusion coefficient; Intralipid solution; glucose concentration Brownian motion; glucose induced Brownian dynamics characterisation; optical coherence tomography; superficial layer; time domain OCT; wavelet power spectrum; Biomedical optical imaging; Optical interferometry; Optical scattering; Optical sensors; Sugar; Wavelet transforms; Brownian diffusion; Optical coherence tomography; turbid media; wavelet;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics (BMEI), 2011 4th International Conference on

Conference_Location

Shanghai

Print_ISBN

978-1-4244-9351-7

Type

conf

DOI

10.1109/BMEI.2011.6098394

Filename

6098394