DocumentCode
2590491
Title
The scoring function based on amino acid network
Author
Jiao, Xiong ; Yang, Lifeng
Author_Institution
Inst. of Appl. Mech. & Biomed. Eng., Taiyuan Univ. of Technol., Taiyuan, China
Volume
4
fYear
2011
fDate
15-17 Oct. 2011
Firstpage
1997
Lastpage
2000
Abstract
With the contact energy between residues as the weight, we constructed a weighted amino acid network. Two parameters are introduced. Based on this network model, we proposed a new docking scoring function Sn. For 42 systems´ bound docking results, we do the scoring sort with this scoring function. Comparing the results got from this new scoring function with that from the RP scoring function, we find that the Sn scoring function has a better performance than the RP on some items.
Keywords
bioinformatics; molecular biophysics; molecular configurations; physiological models; proteins; contact energy; docking scoring function; network model; weighted amino acid network; Amino acids; Bioinformatics; Complex networks; Correlation; Protein engineering; Proteins; Tin; amino acid network; network parameter; protein-protein docking; scorning function; unbound docking;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Engineering and Informatics (BMEI), 2011 4th International Conference on
Conference_Location
Shanghai
Print_ISBN
978-1-4244-9351-7
Type
conf
DOI
10.1109/BMEI.2011.6098684
Filename
6098684
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