• DocumentCode
    2605883
  • Title

    Modelling O2 and CO2 dissociation curves of newborn infants

  • Author

    Lynch, Elizabeth A. ; Waggener, Thomas B.

  • Author_Institution
    Dept. of Biomed. Eng., Boston Univ., MA, USA
  • fYear
    1991
  • fDate
    4-5 Apr 1991
  • Firstpage
    71
  • Lastpage
    72
  • Abstract
    In order to study gas exchange and respiratory control system stability in the newborn period, a model of the O2 and CO2 dissociation curves is developed which incorporates the changes in hemoglobin with age. The model is a modification of Grodin´s equations. The dissociation curves generated by the computer model take into account hematocrit, bicarbonate concentration, pH, barometric pressure, the Bohr effect, the Haldane effect, and the effect of postnatal age on hemoglobin type. They provide improved accuracy in modeling gas exchange and respiratory control system stability in infants
  • Keywords
    biocontrol; blood; physiological models; Bohr effect; CO2; Grodin´s equations; Haldane effect; O2; barometric pressure; bicarbonate concentration; computer model; dissociation curves; gas exchange modeling; hemoglobin; newborn infants; pH; postnatal age; respiratory control system stability; Blood; Equations; High definition video; Pediatrics; Stability;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, 1991., Proceedings of the 1991 IEEE Seventeenth Annual Northeast
  • Conference_Location
    Hartford, CT
  • Print_ISBN
    0-7803-0030-0
  • Type

    conf

  • DOI
    10.1109/NEBC.1991.154585
  • Filename
    154585
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2605883