• DocumentCode
    2684726
  • Title

    Protein is incompressible

  • Author

    Nevill-manning, Craig G. ; Witten, Ian H.

  • Author_Institution
    Rutgers Univ., Piscataway, NJ, USA
  • fYear
    1999
  • fDate
    29-31 Mar 1999
  • Firstpage
    257
  • Lastpage
    266
  • Abstract
    Life is based on two polymers, DNA and protein, whose properties can be described in a simple text file. It is natural to expect that standard text compression techniques would work on biological sequences as they do on English text. But biological sequences have a fundamentally different structure from linguistic ones, and standard compression schemes exhibit disappointing performance on them. We describe a new approach to compression that takes account of the underlying biochemical principles. This gives rise to a generalization of blending for statistical compressors where every context is used, weighted by its similarity to the current context. Results support what research in bioinformatics has shown, that there is little Markov dependency in protein. This cripples data compression schemes and reduces them to order zero models
  • Keywords
    DNA; biology computing; data compression; polymers; proteins; statistical analysis; DNA; biochemical principles; biological sequences; blending; context weighting; order zero models; polymers; protein; similarity weighting; statistical compressors; Bioinformatics; Compressors; Computer science; DNA; Data compression; Databases; Genetic mutations; Organisms; Polymers; Proteins; Sampling methods; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Data Compression Conference, 1999. Proceedings. DCC '99
  • Conference_Location
    Snowbird, UT
  • ISSN
    1068-0314
  • Print_ISBN
    0-7695-0096-X
  • Type

    conf

  • DOI
    10.1109/DCC.1999.755675
  • Filename
    755675