Experimental validation and sensitivity analysis for CFD simulations of cerebral aneurysms

Author

Sun, Qi ; Groth, Alexandra ; Bertram, Matthias ; Waechter, Irina ; Bruijns, Tom ; Hermans, Roel ; Pereira, Vitor Mendes ; Brina, Olivier ; Aach, Til

fYear

2010

fDate

14-17 April 2010

Firstpage

1049

Lastpage

1052

Abstract

In this work, by exploiting a phantom aneurysm model, we illustrate the correlation between experimental data and computational fluid dynamics (CFD) simulation results under well controlled conditions. This is difficult to achieve with clinical patient cases where several uncertainties are present. Quantitative measures are defined for CFD validation by virtual angiography. In addition, a parametric study has been carried out to systematically investigate the sensitivity of current measuring technique on the flow pattern.

Keywords

blood flow measurement; blood vessels; brain; computational fluid dynamics; diagnostic radiography; medical disorders; neurophysiology; phantoms; physiological models; CFD simulations; cerebral aneurysms; computational fluid dynamics simulation; flow pattern; phantom aneurysm model; sensitivity analysis; virtual angiography; Analytical models; Aneurysm; Angiography; Computational fluid dynamics; Computational modeling; Current measurement; Fluid flow control; Imaging phantoms; Parametric study; Sensitivity analysis; Aneurysm; CFD simulation; sensitivity analysis; time intensity curve; validation; virtual angiography;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on

Conference_Location

Rotterdam

ISSN

1945-7928

Print_ISBN

978-1-4244-4125-9

Electronic_ISBN

1945-7928

Type

conf

DOI

10.1109/ISBI.2010.5490170

Filename

5490170