A Two-Layer Model of the Static Behaviour of Blood Vessel Walls

A model is presented that simulates the steady state two-layer nature of blood vessel walls. The model comprises an intimal-medial layer and an adventitial layer, both of which are modeled using previously validated separate models. By including both models, different types of blood vessel can be modeled within a common framework. The necessary relationships that link the two models are presented and simulations of the complete model shown. These illustrate how different types of vessel exhibit different non-linear behaviour. The models include both mechanical and biochemical aspects of the vessel wall behaviour, which will enable the model to be used to simulate more advanced behaviour such as local autoregulatory processes.