A multi-functional online measurement system for neuron-microelectrode interface study

Author

Liang, C.K. ; Chen, D.K. ; Chen, Jia-Jin J. ; Chen, S.C.

Author_Institution

Inst. of Electr. Eng., Southern Taiwan Univ. of Technol., Tainan, Taiwan

Volume

2

fYear

2004

fDate

1-5 Sept. 2004

Firstpage

4100

Lastpage

4102

Abstract

The goal of this paper is to develop a multifunctional measurement system for neuron-microelectrode interface study by LabVIEW. The system uses a commercial 60-channel microelectrode array (MEA) as an interface platform. These online functions of neuronal stimulation, extracellular potential recording, impedance monitoring, and data storage have been integrated into this system. Two offline analysis functions of wavelet de-noising and artifact removing are also included. The former two online functions are executed respectively by a NI-DAQ card and by a self-made analog frond-end amplifier, and Agilent 4284A LCR meter makes the impedance measurement. We have completed the basic functional verifications on a cultured MEA with PC-12.

Keywords

bioelectric potentials; medical computing; microelectrodes; neurophysiology; Agilent 4284A LCR meter; LabVIEW; NI-DAQ card; analog frond-end amplifier; artifact removing; data storage; extracellular potential recording; impedance monitoring; microelectrode array; multifunctional online measurement system; neuron-microelectrode interface; neuronal stimulation; wavelet denoising; Biomedical measurements; Data acquisition; Extracellular; Filters; Hardware; Impedance measurement; Memory; Microelectrodes; Monitoring; Wavelet analysis; i mpedance measurement; microelectrode array (MEA); potential recording; stimulation;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE

Conference_Location

San Francisco, CA

Print_ISBN

0-7803-8439-3

Type

conf

DOI

10.1109/IEMBS.2004.1404144

Filename

1404144