Monitoring of the aggregation phase of erythrocyte sedimentation rate by impedance method on micrometric scale

Author

Tvarozek, Vladimir ; Krausko, Gabriel ; Zahorec, Roman ; Novotny, Ivan ; Rehacek, Vlastimil

Author_Institution

Dept. of Microelectron., Slovak Acad. of Sci., Bratislava, Slovakia

fYear

2000

fDate

2000

Firstpage

387

Lastpage

389

Abstract

The monitoring of the early stage of red blood cells sedimentation by an impedance method using a thin-film interdigitated array of microelectrodes (IDAE) is described. Time dependences of impedance |Z| exhibit maxima which are shifted to the shorter time period for cancer blood samples in comparison with inflammatory ones. Also the impedance rates (time derivate of impedance |Z|) were higher in cancer samples of blood. The sensitivity of this method was getting greater with both the decrease of the IDAE characteristic dimensions from 400 □m down to 5 □m and an increase of temperature from 18°C up to 37°C

Keywords

aggregation; bioelectric phenomena; cellular transport; electric impedance measurement; patient monitoring; sedimentation; 18 C; 37 C; aggregation phase monitoring; cancer samples; characteristic dimensions; erythrocyte sedimentation rate; impedance time dependence; micrometric scale; red blood sedimentation early stage; temperature increase; thin-film interdigitated microelectrodes array; Cancer; Diseases; Gold; Impedance measurement; Microelectrodes; Monitoring; Paramagnetic resonance; Red blood cells; Sputtering; Transistors;

fLanguage

English

Publisher

ieee

Conference_Titel

Microtechnologies in Medicine and Biology, 1st Annual International, Conference On. 2000

Conference_Location

Lyon

Print_ISBN

0-7803-6603-4

Type

conf

DOI

10.1109/MMB.2000.893811

Filename

893811