DocumentCode
2789997
Title
Clustering microarray data using fuzzy clustering with viewpoints
Author
Karayianni, K.N. ; Spyrou, George M. ; Nikita, Konstantina S.
Author_Institution
Sch. of Electr. & Comput. Eng., Nat. Tech. Univ. of Athens, Athens, Greece
fYear
2012
fDate
11-13 Nov. 2012
Firstpage
362
Lastpage
367
Abstract
This paper studies the application of fuzzy clustering with viewpoints in order to cluster cell samples according to their gene expression profile. This method combines fuzzy clustering with external domain knowledge represented by the so-called viewpoints. The viewpoints that we employ are obtained from previously available expression data. The method was compared to the clustering algorithms of k-means, fuzzy c-means, affinity propagation, as well as a method of clustering microarray data that is based on prior biological knowledge, and has shown comparable/improved results over them.
Keywords
biology computing; cellular biophysics; fuzzy set theory; genetics; knowledge representation; lab-on-a-chip; pattern clustering; affinity propagation; biological knowledge; cluster cell samples; external domain knowledge representation; fuzzy c-means clustering algorithm; gene expression profile; k-means clustering algorithm; microarray data clustering; Biology; Cancer; Clustering algorithms; Clustering methods; Indexes; Labeling; Prototypes; Clustering; microarray data; prior knowledge; viewpoints;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics & Bioengineering (BIBE), 2012 IEEE 12th International Conference on
Conference_Location
Larnaca
Print_ISBN
978-1-4673-4357-2
Type
conf
DOI
10.1109/BIBE.2012.6399651
Filename
6399651
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