• DocumentCode
    2789997
  • Title

    Clustering microarray data using fuzzy clustering with viewpoints

  • Author

    Karayianni, K.N. ; Spyrou, George M. ; Nikita, Konstantina S.

  • Author_Institution
    Sch. of Electr. & Comput. Eng., Nat. Tech. Univ. of Athens, Athens, Greece
  • fYear
    2012
  • fDate
    11-13 Nov. 2012
  • Firstpage
    362
  • Lastpage
    367
  • Abstract
    This paper studies the application of fuzzy clustering with viewpoints in order to cluster cell samples according to their gene expression profile. This method combines fuzzy clustering with external domain knowledge represented by the so-called viewpoints. The viewpoints that we employ are obtained from previously available expression data. The method was compared to the clustering algorithms of k-means, fuzzy c-means, affinity propagation, as well as a method of clustering microarray data that is based on prior biological knowledge, and has shown comparable/improved results over them.
  • Keywords
    biology computing; cellular biophysics; fuzzy set theory; genetics; knowledge representation; lab-on-a-chip; pattern clustering; affinity propagation; biological knowledge; cluster cell samples; external domain knowledge representation; fuzzy c-means clustering algorithm; gene expression profile; k-means clustering algorithm; microarray data clustering; Biology; Cancer; Clustering algorithms; Clustering methods; Indexes; Labeling; Prototypes; Clustering; microarray data; prior knowledge; viewpoints;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics & Bioengineering (BIBE), 2012 IEEE 12th International Conference on
  • Conference_Location
    Larnaca
  • Print_ISBN
    978-1-4673-4357-2
  • Type

    conf

  • DOI
    10.1109/BIBE.2012.6399651
  • Filename
    6399651