Ex vivo and in vivo oral cancer diagnosis using backward-collected third harmonic generation biopsy

Author

Tai, Shih-Peng ; Shieh, Dar-Bin ; Lee, Wen-Jeng ; Yu, Che-Hang ; Wu, Ping-Ching ; Wu, Yana ; Sun, Chi-Kuang

Author_Institution

Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei

fYear

2006

fDate

21-26 May 2006

Firstpage

1

Lastpage

2

Abstract

Ex vivo and in vivo oral cancer diagnoses are demonstrated using noninvasive third-harmonic-generation biopsy. Through its superior spatial resolution on nucleus, oral cancer cells in hamster oral cavities are successfully identified without any exogenous markers.

Keywords

biomedical optical imaging; cancer; cellular biophysics; image resolution; optical harmonic generation; tumours; backward-collected third harmonic generation biopsy; cell nucleus; ex vivo oral cancer diagnosis; hamster oral cavities; in vivo oral cancer diagnosis; noninvasive diagnosis; oral cancer cells; spatial resolution; Biomedical optical imaging; Biopsy; Cancer; Fluorescence; Frequency conversion; In vivo; Nonlinear optics; Optical harmonic generation; Optical microscopy; Ultrafast optics; (180.6900) Three-dimensional microscopy; (190.4160) Mutiharmonic generation;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics, 2006 and 2006 Quantum Electronics and Laser Science Conference. CLEO/QELS 2006. Conference on

Conference_Location

Long Beach, CA

Print_ISBN

978-1-55752-813-1

Electronic_ISBN

978-1-55752-813-1

Type

conf

DOI

10.1109/CLEO.2006.4628199

Filename

4628199