Multi-agent Based Bioinformatics Integration Using Distributed Dynamic Description Logics

Integration of bioinformatics data repositories is a challenging task in which data sets are usually heterogeneous in structure and are often distributed across multiple, autonomously maintained databases. In this context, we present an innovative system which coordinates bioinformatics data by combining P2P data integration paradigm and Distributed Dynamic Description Logics (D3L) on top of Multi-Agent System infrastructure. We define the semantics and syntax of D3L, and propose a distributed consistency checking algorithm for realizing the intelligent query with logical reasoning function and decomposing large tasks to sub-tasks that could be tackled by different agents. Finally, we introduce a prototype implementation and present its evaluation. The results indicate that the proposed approach achieves excellent robustness and satisfactory performance.