• DocumentCode
    2918444
  • Title

    Evolving scale-free topologies using a Gene Regulatory Network model

  • Author

    Nicolau, Miguel ; Schoenauer, Marc

  • Author_Institution
    INRIA Saclay, Univ. Paris Sud, Orsay
  • fYear
    2008
  • fDate
    1-6 June 2008
  • Firstpage
    3747
  • Lastpage
    3754
  • Abstract
    A novel approach to generating scale-free network topologies is introduced, based on an existing artificial Gene Regulatory Network model. From this model, different interaction networks can be extracted, based on an activation threshold. By using an Evolutionary Computation approach, the model is allowed to evolve, in order to reach specific network statistical measures. The results obtained show that, when the model uses a duplication and divergence initialisation, such as seen in nature, the resulting regulation networks not only are closer in topology to scale-free networks, but also exhibit a much higher potential for evolution.
  • Keywords
    complex networks; evolutionary computation; topology; activation threshold; artificial gene regulatory network model; divergence initialisation; duplication; evolutionary computation approach; network statistical measures; scale-free topologies; Bioinformatics; Biological system modeling; Computational modeling; Evolution (biology); Evolutionary computation; Genomics; Network topology; Power generation; Proteins; Wiring;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2008. CEC 2008. (IEEE World Congress on Computational Intelligence). IEEE Congress on
  • Conference_Location
    Hong Kong
  • Print_ISBN
    978-1-4244-1822-0
  • Electronic_ISBN
    978-1-4244-1823-7
  • Type

    conf

  • DOI
    10.1109/CEC.2008.4631305
  • Filename
    4631305