DocumentCode
2918444
Title
Evolving scale-free topologies using a Gene Regulatory Network model
Author
Nicolau, Miguel ; Schoenauer, Marc
Author_Institution
INRIA Saclay, Univ. Paris Sud, Orsay
fYear
2008
fDate
1-6 June 2008
Firstpage
3747
Lastpage
3754
Abstract
A novel approach to generating scale-free network topologies is introduced, based on an existing artificial Gene Regulatory Network model. From this model, different interaction networks can be extracted, based on an activation threshold. By using an Evolutionary Computation approach, the model is allowed to evolve, in order to reach specific network statistical measures. The results obtained show that, when the model uses a duplication and divergence initialisation, such as seen in nature, the resulting regulation networks not only are closer in topology to scale-free networks, but also exhibit a much higher potential for evolution.
Keywords
complex networks; evolutionary computation; topology; activation threshold; artificial gene regulatory network model; divergence initialisation; duplication; evolutionary computation approach; network statistical measures; scale-free topologies; Bioinformatics; Biological system modeling; Computational modeling; Evolution (biology); Evolutionary computation; Genomics; Network topology; Power generation; Proteins; Wiring;
fLanguage
English
Publisher
ieee
Conference_Titel
Evolutionary Computation, 2008. CEC 2008. (IEEE World Congress on Computational Intelligence). IEEE Congress on
Conference_Location
Hong Kong
Print_ISBN
978-1-4244-1822-0
Electronic_ISBN
978-1-4244-1823-7
Type
conf
DOI
10.1109/CEC.2008.4631305
Filename
4631305
Link To Document