• DocumentCode
    2931650
  • Title

    Microarray Classification and Rule Based Cancer Identification

  • Author

    Nahar, Jesmin ; Chen, Yi-Ping Phoebe ; Ali, ABM Shawkat

  • Author_Institution
    Deakin Univ., Deakin
  • fYear
    2007
  • fDate
    7-9 March 2007
  • Firstpage
    43
  • Lastpage
    46
  • Abstract
    Microarray analysis creates a clear scenario for the complete transcription profile of cells that facilitate drug and therapeutics development, disease diagnosis and enable us to take an in depth look at cell biology. One of the key challenges in microarray analysis, especially in cancerous gene expression profiles, is to identify genes or groups of genes that are highly responsible for the existence of a tumor in a cell. Our proposed modified algorithm support vector machine (SVM) is used to classify cancer related 5 microarray data and observed improved performance than previously used Interesting rule group (IRG), classification based on associations (CBA), and even a different version of SVM algorithm. Finally we use entropy measure through rule based learning algorithm to extract the responsible genes causes for cancer for each microarray problem. The rules are generated with higher acceptability.
  • Keywords
    biology computing; cancer; knowledge based systems; learning (artificial intelligence); support vector machines; cancerous gene expression profiles; disease diagnosis; drug; entropy measure; micro array classification; rule based cancer identification; rule based learning algorithm; support vector machine; therapeutics development; transcription profile; Biological cells; Cancer; Cells (biology); Diseases; Drugs; Entropy; Gene expression; Neoplasms; Support vector machine classification; Support vector machines;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information and Communication Technology, 2007. ICICT '07. International Conference on
  • Conference_Location
    Dhaka
  • Print_ISBN
    984-32-3394-8
  • Type

    conf

  • DOI
    10.1109/ICICT.2007.375339
  • Filename
    4261362