Simulation of cardiac RR interval time series

Author

Bowers, E.J. ; Langley, P. ; Drinnan, M.J. ; Allen, J. ; Smith, F.E. ; Murray, A.

Author_Institution

Regional Med. Phys. Dept., Freeman Hosp., Newcastle upon Tyne, UK

fYear

2002

fDate

22-25 Sept. 2002

Firstpage

233

Lastpage

236

Abstract

An RR interval simulator was developed as part of the Computers in Cardiology Challenge (entry no. 184). The simulator was based on observed physiological changes in normal subjects. A template, which represented slow trends in RR interval during 24 hours, was derived from a number of parameters that represent sleep and wake states. The variations about the template were generated so that the frequency spectrum of the final signal was similar to data from normal subjects. The frequency spectrum of normal RR intervals shows a strong 1/f component, a peak at around 0.1 Hz and a peak corresponding to respiratory rate between 0.15 Hz and 0.4 Hz. These were simulated by adding to the template pink noise, a number of random phased sinusoids at around 0.1 Hz and a signal that represented respiration. Variations due to respiration were dependent on sleep and wake states.

Keywords

bioelectric potentials; cardiology; digital simulation; medical computing; physiological models; time series; Computers in Cardiology Challenge; RR interval simulator; cardiac RR interval time series; frequency spectrum; normal subjects; physiological changes; random phased sinusoids; respiratory rate; sleep states; wake states; 1f noise; Cardiology; Computational modeling; Computer simulation; Frequency; Hospitals; Iron; Medical simulation; Physics; Sleep;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 2002

ISSN

0276-6547

Print_ISBN

0-7803-7735-4

Type

conf

DOI

10.1109/CIC.2002.1166750

Filename

1166750