• DocumentCode
    2989636
  • Title

    Identifying duplications and lateral gene transfers simultaneously and rapidly

  • Author

    Zhi-Zhong Chen ; Fei Deng ; Lusheng Wang

  • Author_Institution
    Dept. of Inf. Syst. Design, Tokyo Denki Univ., Tokyo, Japan
  • fYear
    2013
  • fDate
    16-19 April 2013
  • Firstpage
    128
  • Lastpage
    135
  • Abstract
    This paper deals with the problem of enumerating all minimum-cost LCA-reconciliations involving gene duplications and lateral gene transfers (LGTs) for a given species tree S and a given gene tree G. Previously, Tofigh et al. [20] gave a fixed-parameter algorithm for this problem that runs in O(m + 3k n) time, where m is the number of vertices in S, n is the number of vertices in G, and k is the minimum cost of an LCA-reconciliation between Sand G. In this paper, by refining their algorithm, we obtain a new one for the same problem that finds and outputs the solutions in a compact form within O(mn2 + 3k) time.
  • Keywords
    biology computing; evolution (biological); genetics; fixed-parameter algorithm; gene duplications; gene tree; lateral gene transfers; minimum-cost LCA-reconciliations; Binary trees; Bioinformatics; Computational biology; Educational institutions; Electronic mail; Junctions; Vegetation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 2013 IEEE Symposium on
  • Conference_Location
    Singapore
  • Type

    conf

  • DOI
    10.1109/CIBCB.2013.6595398
  • Filename
    6595398