DocumentCode
2997522
Title
Development of a fiber optic-based CARS exoscope for the in vivo study of spinal cord disorders
Author
Murugkar, Sangeeta ; Smith, Brett ; Brideau, Craig ; Stys, Peter ; Anis, Hanan
Author_Institution
Sch. of Inf. Technol. & Eng. (SITE), Univ. of Ottawa, Ottawa, ON, Canada
fYear
2011
fDate
7-8 April 2011
Firstpage
96
Lastpage
99
Abstract
This paper describes our development of a fiber optic, MEMS-scanning based multimodal miniature microscope for in vivo nonlinear optical imaging of the spinal cord. The novel design of the exoscope will enable serial examinations of the status of the myelin sheath over time in the same animal by means of CARS microscopy. The basic design concept, major engineering challenges, solutions, and some preliminary results are presented.
Keywords
bioMEMS; biomedical equipment; biomedical optical imaging; coherent antiStokes Raman scattering; fibre optic sensors; microsensors; neurophysiology; optical microscopes; MEMS-scanning; fiber optic-based CARS exoscope design; in vivo nonlinear optical imaging; multimodal miniature microscope; myelin sheath; spinal cord disorder; Microscopy; Mirrors; Optical fibers; Optical imaging; Spinal cord;
fLanguage
English
Publisher
ieee
Conference_Titel
Life Science Systems and Applications Workshop (LiSSA), 2011 IEEE/NIH
Conference_Location
Bethesda, MD
Print_ISBN
978-1-4577-0421-5
Type
conf
DOI
10.1109/LISSA.2011.5754165
Filename
5754165
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