The Comparison of Haplotype Difference Based on the 21st Chromosome of Four Populations

Author

Pei, Zhili ; Zhou, Yuxin ; Liu, Lisha ; Wang, Lihua ; Lu, Yinan ; Kong, Ying

Author_Institution

Coll. of Comput. Sci. & Technol., Inner Mongolia Univ. for the Nationalites, Tongliao, China

fYear

2010

fDate

25-27 June 2010

Firstpage

2275

Lastpage

2278

Abstract

Single nucleotide polymorphisms are the most plentiful genetic variations of human genome. Haplytype is a group of interrelated SNP allele loci, which are located at one chromosome or certain regions. It has been the important composition of human genetic research in recent years. In the research on complex disease, the analysis of haplotype composed by many SNP loci is superior to the analysis of one SNP locus. In this paper, through the processing of genotype data provided by Hapmap project, the haplotype data of 21st chromosome of four populations are obtained. The haplotype difference of four populations is also obtained by the reasonable comparing algorithms.

Keywords

diseases; genetics; 21st chromosome; complex disease; haplotype difference; human genetic research; human genome; interrelated SNP allele loci; single nucleotide polymorphisms; Bioinformatics; Biological cells; DNA; Diseases; Genomics; Humans; Haplotype; SNPs; complex disease Introduction; infective genes;

fLanguage

English

Publisher

ieee

Conference_Titel

Electrical and Control Engineering (ICECE), 2010 International Conference on

Conference_Location

Wuhan

Print_ISBN

978-1-4244-6880-5

Type

conf

DOI

10.1109/iCECE.2010.561

Filename

5631968