Ultrasonic molecular imaging of primordial angiogenic vessels in the papilloma virus transgenic mouse with αvβ3-integrin targeted nanoparticles using Renyi entropy-based signal detection

Author

Wallace, Kirk D. ; Marsh, Jon N. ; Thomas, Lewis J., III ; Neuman, Robert G. ; Arbeit, Jeffery M. ; Lanza, Gregory M. ; Wickline, Samuel A.

Author_Institution

Sch. of Med., Washington Univ. in St. Louis, Saint Louis, MO

fYear

2008

fDate

2-5 Nov. 2008

Firstpage

367

Lastpage

370

Abstract

Previously we reported on an entropy-based signal receiver and demonstrated that, in certain settings, it was more sensitive to subtle changes in scattering architecture than conventional energy-based signal characterization. In this paper we present results demonstrating further improvements in sensitivity using a signal receiver based on the Renyi-entropy.

Keywords

biomedical ultrasonics; entropy; medical signal detection; microorganisms; nanobiotechnology; nanoparticles; Renyi entropy-based signal detection; alpha_vbeta₃-integrin targeted nanoparticles; papilloma virus transgenic mouse; primordial angiogenic vessels; ultrasonic molecular imaging; Biomedical imaging; Density functional theory; Energy measurement; Entropy; Hafnium; Mice; Molecular imaging; Nanoparticles; Radio frequency; Signal processing; HPV mouse; Renyi entropy; information-theoretic detector; molecular imaging; targeted nanoparticle;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 2008. IUS 2008. IEEE

Conference_Location

Beijing

Print_ISBN

978-1-4244-2428-3

Electronic_ISBN

978-1-4244-2480-1

Type

conf

DOI

10.1109/ULTSYM.2008.0090

Filename

4803562