DocumentCode
3025541
Title
A mathematical model simulating disease treatment: S.L.E.
Author
Merrill, S.J.
Author_Institution
Marquette University, Milwaukee, Wisconsin
fYear
1979
fDate
10-12 Jan. 1979
Firstpage
750
Lastpage
754
Abstract
A model of B-lymphocyte stimulation and associated antibody production is used to simulate treatment and the course of Systematic lupus erythematosis (SLE). Some of the most severe symptoms of the disease are thought to be consequences of the production of antibody against our own DNA(SLE is an "autoimmune" disease). Treatment consists of minimizing organ damage by suppressing the production of antibody (by suppressing all the components of the immune response) and maintaining the patient in a stable condition. The effect of treatment in use and the existence of a stable equilibrium is demonstrated in the model.
Keywords
Continuous production; Diseases; Mathematical model; Proteins; Statistics;
fLanguage
English
Publisher
ieee
Conference_Titel
Decision and Control including the 17th Symposium on Adaptive Processes, 1978 IEEE Conference on
Conference_Location
San Diego, CA, USA
Type
conf
DOI
10.1109/CDC.1978.268026
Filename
4046213
Link To Document