DocumentCode
3073326
Title
The MAPK Signal Pathway Research and New Drug Discovery
Author
Chen, Po-Yuan ; Jhuo, Mien-De ; Hsu, W.-T. ; Shih, Tzu-Ching ; Cheng, Tzu-Humg
Author_Institution
Dept. of Biol. Sci. & Technol., China Med. Univ., Taichung, Taiwan
fYear
2009
fDate
22-24 June 2009
Firstpage
370
Lastpage
373
Abstract
MAPK cell signal transduction pathways determine the survival of the cells. If one can control this pathways, and then they will prohibit the proliferation of the cancer cells. Furthermore, they will heal the cancer smoothly. In order to attain this goal, we use lots of drugs to interact with MEK1 in MAPK, by using computer aided drug design to analyze the ligand activity of proteins in MEK1.
Keywords
bioinformatics; cancer; cellular biophysics; chemistry computing; drugs; molecular biophysics; proteins; tumours; MAPK cell signal transduction pathways; MAPK signal pathway research; MEK1 interactions; cancer cell proliferation; cancer healing process; cell survival determination; computer aided drug design; drug discovery; protein ligand activity; Bioinformatics; Biomedical engineering; Bonding; Cancer; Cells (biology); Drugs; Hospitals; Pharmaceutical technology; Proteins; Radiology; Docking; MAPK;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and BioEngineering, 2009. BIBE '09. Ninth IEEE International Conference on
Conference_Location
Taichung
Print_ISBN
978-0-7695-3656-9
Type
conf
DOI
10.1109/BIBE.2009.80
Filename
5211245
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