Diagnosis of tissue pathology with elastic scattering spectroscopy

Author

Mourant, J.R. ; Bigio, I.J. ; Boyer, J. ; Lacey, J. ; Johnson, T. ; Conn, R.L. ; Bohorfousch, A.G. ; Ross, A.B.

Author_Institution

Los Alamos Nat. Lab., NM, USA

Volume

1

fYear

1994

fDate

31 Oct-3 Nov 1994

Firstpage

17

Abstract

An optical biopsy system based on elastic-scatter spectroscopy has been developed. This system uses white light excitation, is relatively inexpensive, endoscopically compatible, and portable. Light is delivered to the tissue by one or more optical fibers. The OBS has been tested on bladder cancer with excellent results. Preliminary data on the usefulness of the OBS to diagnose dysplasia in the esophagus and detect adenomatous polyps indicate that the OBS may also be useful in these arenas

Keywords

patient diagnosis; 300 to 900 nm; 345 to 380 nm; 500 to 700 nm; adenomatous polyps; bladder cancer; dysplasia; elastic scattering spectroscopy; esophagus; inexpensive endoscopically compatible portable system; optical biopsy system; optical fibers; tissue pathology diagnostics; white light excitation; Biomedical optical imaging; Biopsy; Bladder; Cancer; Light scattering; Optical fibers; Optical scattering; Pathology; Spectroscopy; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Lasers and Electro-Optics Society Annual Meeting, 1994. LEOS '94 Conference Proceedings. IEEE

Conference_Location

Boston, MA

Print_ISBN

0-7803-1470-0

Type

conf

DOI

10.1109/LEOS.1994.586869

Filename

586869