Evaluation of Silicon and Polymer substrates for fabrication of integrated microfluidic microsystems for DNA extraction and amplification

Author

Gheorghe, M. ; Blionas, S. ; Ragoussis, J. ; Galvin, P.

Author_Institution

Tyndall Nat. Inst., Cork

fYear

2006

fDate

Aug. 30 2006-Sept. 3 2006

Firstpage

2482

Lastpage

2485

Abstract

This paper is presenting two different alternatives for the DNA extraction and amplification that will be carried out by two competitive research projects developing bioanalytical microsystems with microfluidics. The first project will develop the microfluidics part on polymer material and the other one on silicon. The polymer approach is currently under development based on a modular microfluidic architecture aimed to simplify the process of designing and building such a microsystem device. A silicon alternative is about to start and is expected to decrease packaging costs of the microsystem allowing future manufacturability of the device

Keywords

DNA; biological techniques; genetics; microfluidics; polymers; silicon; substrates; DNA amplification; DNA extraction; Si; bioanalytical microsystem; integrated microfluidic microsystem device fabrication; modular microfluidic architecture; packaging cost; polymer material; polymer substrates; silicon substrates; Biological materials; Buildings; Costs; DNA; Fabrication; Microfluidics; Packaging; Polymers; Process design; Silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE

Conference_Location

New York, NY

ISSN

1557-170X

Print_ISBN

1-4244-0032-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2006.259931

Filename

4462298